Wild-type mice | Cx32-deficient mice | Difference (in %) | |
---|---|---|---|
Values given as mean ± SD; *significantly different at the 5% level; NS, not significant. | |||
aWithout cerebellum and brain stem (cf. Materials and methods). | |||
bShort diameter of axon profiles (cf. Materials and methods). | |||
Body weight (in g) (n = 4 mice) | 29.71 ± 3.30 | 24.55 ± 2.31 | 17.4* (P = 0.043) |
Brain weighta (in g) (n = 4 mice) | 0.36 ± 0.01 | 0.33 ± 0.01 | 8.3* (P = 0.0005) |
Thickness of neocortex (in μm, n = 30 sections, 3 mice) | 1250.87 ± 68.91 | 1104.04 ± 24.07 | 11.7 (NS) |
Number of axons per μm2 (n = 3 mice) | 0.55 ± 0.07 | 0.46 ± 0.06 | 16.4 (NS) |
Diameterb of axons (in μm, n = 100 axons, 3 mice) | 0.49 ± 0.01 | 0.46 ± 0.03 | 4.1 (NS) |
Thickness of myelin sheath (in μm, n = 100 axons, 3 mice) | 0.15 ± 0.01 | 0.13 ± 0.01 | 13.3* (P = 0.023) |
Volume fraction of myelin (in %, n = 3 mice) | 17.43 ± 1.12 | 14.13 ± 1.36 | 18.9* (P = 0.031) |
Article: Myelination defects and neuronal hyperexcitability in the neocortex of connexin 32-deficient mice.
Full Text (publisher's website) ; Article Metadata ; Article Data (extracted) Sutor B; Schmolke C; Teubner B; Schirmer C; Willecke K Cereb. Cortex, 2000
Inferred neuron-electrophysiology data values
Neuron Type | Neuron Description | Ephys Prop | Extracted Value | Standardized Value | Content Source |
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